The Delta Gateway Museum provides free, heritage-based, cultural and educational opportunities for regional school children, senior citizens, heritage tourists and tour groups, and the general public.
The museum collects, stores, maintains, and regularly exhibits historical and cultural objects, artifacts, photographs, works of art, printed materials, and audio-visual materials that relate to and emphasize the history and cultural development of Blytheville, Mississippi County, Northeast Arkansas and the Arkansas Delta.
Prehistoric and early historic Native American cultures
The growth and impact of Euro-American and African-American settlement
The importance of the timber industry and swamp drainage in the development of cotton agriculture
The development and regional significance of river, rail and highway transportation
The historical effects and continuing threat of earthquakes and flooding
The regional impact of the air force base and steel industry
The museum provides an introduction to other parts of the Arkansas delta.
The Delta Gateway Museum occupies the historic S. H. Kress Building, located in the Blytheville Commercial Historic District. The Kress Building was listed on the National Register of Historic Places in 1997.